| Trusted by 10K+ customers | 14 Servings

Microbiome-First Longevity Support

Longevity is a precision-formulated, bio-fermented triple-biotic blend combining live cultures with polyphenol-rich botanical ingredients. A considered formulation built on strain specificity, ingredient quality, and bioavailability.

See It In Action

🔊
Flavour:

Flavour Guarantee

Not the perfect Flavour? We’ll change it within 24 hours

Subscribe & Save:

Subscriptions
Bundle and Save BEST VALUE
EXTRA 15% OFF

12-Week Programme + Your Add-On + 4 Free Gifts

Microbiome-First Longevity Support

12-Week
Programme

$834.00$599.97

+

Total: $509.97 — You save $90.00

FREE Express shipping on subscriptionsFREE Express shipping on subscriptions
100% money back guarantee100% money back guarantee
Researched ingredientsResearched ingredients

At the centre of the formula is evaBiome™ EternaGen Polyphenol Complex a bio-fermented polyphenol blend paired with a multi-strain culture complex delivering 60 billion live cultures and 10 billion postbiotic metabolites per serve. A considered formulation focused on strain specificity, ingredient quality, and consistent daily use.


Simple. Consistent. Foundational.
Take 1 sachet daily

Mix with 200–250ml of cold water.
On an empty stomach or before your first meal for optimal microbiome support.*

Stay consistent
Designed for daily, long-term use to support healthy biological ageing.


evaBiome™ EternaGen Polyphenol Complex:
A next-generation, bio-fermented polyphenol system delivering:

  • Bioavailable polyphenols
  • Antioxidants
  • Postbiotic metabolites

Designed to support gut, immune, and brain vitality through advanced fermentation and biomolecular optimisation.

Blue Zone Probiotic Complex:
A scientifically researched probiotic blend delivering:

  • 60 billion live probiotics
  • 10 billion postbiotics per serve

Featuring strains shown to support microbial balance, gut-barrier integrity, and inflammatory regulation.

Triple-Biotic Synergy (Pre • Pro • Post):
A complete system designed to:

  • Nourish beneficial bacteria
  • Restore microbiome diversity

Strengthen gut-barrier function



  • Source of live cultures and polyphenol-rich ingredients
  • Considered formulation with transparent dosing
  • Free from fillers and artificial additives
  • Supports general health and wellbeing

Microbiome shifts begin. Digestive balance and inflammatory regulation support starts at the gut level.*

Weeks 3–6
Cellular antioxidant activity and resilience pathways strengthen.*

Ongoing
Supports sustained clarity, vitality, and healthy inflammatory response as part of your daily routine.*


★★★★★
About three weeks in and I genuinely feel more energised during the day. I originally bought this for inflammation support but the steady energy has been the biggest surprise.
★★★★★
I’m really impressed with this formula. My body just feels better overall - less stiffness in the morning and better recovery after workouts - another great product Calmerceuticals.
★★★★★
I’ve been focusing on longevity and health recently and this product was recommended to me. I could feel it by about day 8 - a lot less bloated and like my body had let go of a lot of fluid. Love the ingredients and the science behind it.
[{"variant_id":"44550522011741" , "metafield_value":""},{"variant_id":"44550522044509" , "metafield_value":""},{"variant_id":"44550522077277" , "metafield_value":""},{"variant_id":"44223159140445" , "metafield_value":""},{"variant_id":"44223159173213" , "metafield_value":""},{"variant_id":"44240054616157" , "metafield_value":""},{"variant_id":"44223163105373" , "metafield_value":""},{"variant_id":"44223163138141" , "metafield_value":""},{"variant_id":"44240054648925" , "metafield_value":""}]
Microbiome-First Longevity Support

Microbiome-First Longevity Support

Money-back guarantee, Free shipping, Scientifically trialled ingredients

Hear from people
who are already using our product

Don't just take our word for it, see what our customers say

I feel more balanced and energized throughout the day. It’s made a real difference in my routine.

-Sarah Collins

Better sleep, improved focus, and overall well-being—I feel healthier from within.

-Natalie

My energy levels are more consistent, and I just feel more in control of my health.

-EMILY

“I’ve noticed steady improvements in vitality and recovery. Feels like a smart long-term investment.

-Isabella

Formulated with researched bio-fermented polyphenols and triple-biotic synergy.

Evidence-driven formulation Published research on the hero ingredient complex show.

Precision Longevity System

Rewrite
Your Age.

World's First

The world's first microbiome catalyst shown to reduce biological inflammageing markers by up to 90% within 14 days*. Engineered from centenarian-sourced probiotics.

*Studies conducted on the ingredient complex; not on Calmerceuticals Longevity as a finished product. Individual results may vary.

START YOUR 14-DAY REJUVENATION

Calmerceuticalsis loved by thousands

When inflammation stays
elevated

cellular repair declines, metabolic balance falters, and biological ageing accelerates

Real results you
can see and feel.

Product image
80%
Improvement in learning and memory performance
2 weeks
Within 2 weeks, inflammatory markers improved by up to 90%
67%
boost in brain antioxidant protection

Ageing isn't driven by time.
It's driven by biology
under stress.

Inflammageing is the chronic, low-grade inflammation that silently accelerates biological decay, disrupts mitochondrial function, weakens gut-barrier integrity, and contributes to systemic immune stress long before symptoms appear.


Most supplements address surface-level outcomes. Longevity is formulated to support the gut-brain-immune axis the biological network that underpins inflammation, cellular energy, and healthy ageing.

Background

Short-chain fatty acids increased by up to 2x

67%
boost in brain antioxidant protection

Longevity is systemic. When the core biological pathways that govern energy, inflammation, and repair are supported consistently, resilience strengthens over time

START YOUR REJUVENATION START YOUR REJUVENATION START YOUR REJUVENATION START YOUR REJUVENATION

Longevity is built through consistency, not intensity.

Background

Gut
Balance

Supports microbiome diversity and strengthens gut barrier integrity, a foundation for immune and metabolic health.

Cellular
Energy

Postbiotics and polyphenols support healthy mitochondrial function and sustained cellular energy production.

Oxidative
Defence

Antioxidants help protect cells from daily oxidative stress, supporting long-term cellular resilience.

Vitality &
Resilience

Supports clarity, sustained energy, and the biological systems linked to healthy ageing.

Radical Transparency

Simple ingredients,
powerful results.

We believe you deserve to see the exact strains, doses, and scientific trial matches behind every sachet. No proprietary blends. No hiding behind "complexes."

Product
Active Ingredients
evaBiome™ EternaGen Polyphenol Complex
Blue Zone Probiotic Complex
60B
Postbiotics
10B
Bio-Fermented Polyphenols
Triple-Biotic System
Pre • Pro • Post
START YOUR REJUVENATION START YOUR REJUVENATION

Icon
Nourish 01

Biofermented polyphenols from olives, tea, and cocoa create the precise gut environment for centenarian strains to thrive and proliferate.

Icon
Repair 02

Fermentation-derived metabolites including short-chain fatty acids and urolithins reinforce the gut barrier and trigger mitophagy for cellular renewal.

1,450 verified 5 star reviews

All reviews

“About three weeks in and I genuinely feel more energised during the day. I originally bought this for inflammation support but the steady energy has been the biggest surprise.”

“I’m really impressed with this formula. My body just feels better overall - less stiffness in the morning and better recovery after workouts - another great product Calmerceuticals ”

“I’ve been focusing on longevity and health recently and this product was recommended to me. I could feel it by about day 8 - a lot less bloated and like my body had let go of a lot of fluid. Love the ingredients and the science behind it.”

The Rejuvenation Roadmap

Biological transformation,
mapped to the hour.

HOUR 8
ViaCap™ Absorption

Micro-encapsulated probiotics bypass stomach acid and reach the colon intact. Initial colonization begins.

DAY 2
Mitophagy Activation

Postbiotic metabolites trigger cellular housekeeping. Damaged mitochondria are cleared and renewed.

DAY 14
Biological Age Reversal

IL-6, CRP, and TNF-α markers reach improvement thresholds. Gut barrier integrity restored.

DAY 120
Peak Physical Strength

Mitochondrial density at optimal levels. Energy biogenesis sustains performance throughout the day.

DAY 365
Optimal Cellular Health

Microbiome diversity matches centenarian profiles. Systemic inflammageing markers sustained in optimal range.

Product

It's not magic,
It's science

When our bodies are under constant stress, they produce chronic, low-grade inflammation that never fully turns off.

That "biological fire" is largely responsible for the cognitive dullness, metabolic resistance, and persistent fatigue we often mistake for "just getting older".

As these "cellular batteries" wear out, they stop producing energy and start producing "cellular rust" (oxidative stress). This decay is the primary reason your "Health Span" feels shorter than your actual years, leading to a body that performs below its potential.

A "metabolically old" system accumulates specific markers like BCAAs and Lysine, which are linked to systemic resistance and inflammation. By lowering these metabolic signatures and doubling your production of Short-Chain Fatty Acids (SCFAs), we provide the clean cellular fuel required for the sustained vitality of a younger body.

Available Flavours

Watermelon Crush
Watermelon Crush
Pink Lemonade
Pink Lemonade

You probably have questions

Here are the ones we get asked most. If yours isn't here, reach out directly.

All FAQs

Most products address symptoms. Longevity targets the system behind them. The studied ingredients in our formula are designed to restore microbiome diversity, reinforce gut barrier integrity, and regulate inflammatory signalling — three of the most well-documented drivers of accelerated biological ageing. When these systems function correctly, the body shifts from defence mode into repair mode.

Studies conducted on individual ingredients, not on the Calmerceuticals finished product. Individual results may vary.

Our strains are isolated from the gut microbiomes of verified centenarians living in established longevity regions. These organisms have co-evolved with long-lived human biology in ways that commercially farmed strains cannot replicate. We source from populations, not laboratories.

Biological resilience compounds over time. Most people notice improvements in gut comfort, energy, and cognitive clarity within the first few weeks. Measurable changes to microbiome diversity and inflammatory regulation typically develop over a consistent 90-day period, and the data suggests these changes persist well beyond supplementation.

Studies conducted on individual ingredients, not on the Calmerceuticals finished product. Individual results may vary.

Standard delivery formats expose probiotics to stomach acid, destroying the majority before they reach their target site. Longevity uses a micro-encapsulated delivery system designed to ensure 95% colon survivability, so the strains you're taking are the strains that arrive.

Longevity is formulated with researched ingredients at safe, effective doses. If you are taking prescription medications or managing a health condition, we recommend consulting your healthcare provider before starting any new supplement system.

Studies conducted on individual ingredients, not on the Calmerceuticals finished product. Individual results may vary.

Recommended plan

Balance your nights with better mornings

Bio-fermentation enhances nutrient bioavailability and functional activity in the gut.

Advanced biomanufacturing improves delivery, stability, and efficacy – so the body can actually use what you take.


This is proactive ageing support, not damage control.

12 Week Performance Reset
Balance your nights with better mornings